, 2007
 
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Sleep Disordered Breathing in Children (SDB)
[Information provided by Kevin D. Pereira, M.D., and Michael D. Poole, M.D.]

 

Basic Facts

  • Prevalence - between 1 and 11%
  • Simple snoring is more common than sleep apnea and thought to be without any adverse effects.
  • Majority of the children with snoring do not have sleep apnea.
  • African-Americans are more prone to this condition when compared to Caucasians.
  • Sleep disordered breathing in children includes:
    • Obstructive sleep apnea (OSA)
    • Upper airway resistance syndrome (UARS)
    • Primary snoring

 

What is the cause?

Obstructive sleep apnea in children is usually due to swelling of the tonsils and adenoids. The volume of this tissue in the upper airway increases from around six months of age up to puberty, with the maximum proliferation occurring in the preschool years. This age coincides with the peak incidence of OSA in children.

Obesity as a cause of OSA is increasing in frequency, especially in school age children.

Abnormal craniofacial developments such as Pierre Robin sequence, Treacher Collin's, Apert's and Crouzon's syndromes and neuromuscular abnormalities such as cerebral palsy and anoxic encephalopathy have a much higher incidence of severe OSA. Children with allergies are more likely to have habitual snoring. The swelling of the nasal mucosa along with increased secretions causes airway obstruction during sleep.

 

What happens in obstructive sleep apnea?

There is cyclical upper airway obstruction causing hypoxia (lowering of oxygen saturation in blood) and hypercapnea (retention of carbon dioxide). This usually occurs during deeper levels of sleep and results in an arousal causing fragmentation and disruption of normal sleep.

 

What are the possible adverse effects of OSAS?

  • Mouth breathing and hyponasal speech with articulatory errors
  • Decreased school performance in children.
  • Hyperactivity, attention deficit, aggression and other behavioral disorders
  • Higher blood pressures
  • Nocturnal enuresis (bedwetting)
  • Failure to thrive due to a combination of poor appetite, impaired growth hormone secretion and/or increased work of breathing

Severe cases may progress to cardiopulmonary dysfunction.

 

What tests are available and do they have to be done?

Sleep studies remain the gold standard for the diagnosis of OSA in adults and children.

However, a good history and physical examination by a skilled clinician can identify most cases of sleep apnea in children. Sleep studies are generally used in very young children and when in doubt about the diagnosis.

Overnight PSG can be performed at home or in the sleep laboratory. Daytime "nap studies" and nighttime pulse oximetry have fair positive predictive value, but cannot exclude the presence of significant sleep apnea.

Audio and/or video recordings and their analyses may be able to confirm severe sleep apnea but cannot differentiate mild OSA from primary snoring. Soft tissue radiographs of the nasopharynx have limited use in assessing adenoid enlargement when compared to flexible endoscopy.

 

What values would be considered abnormal in a pediatric sleep study?

  • Apnea index of >1
  • Oxygen desaturation of >4% more than three times an hour or associated with a >25% change in heart rate
  • Oxygen desaturation <92%
  • Elevation of end-tidal CO2 to >50mm/hg for >8% of total sleep time or 45mm/hg for >60% of sleep time

What is the treatment?

Medical therapy with nasal steroids may help some, especially those with allergies. Adenotonsillectomy remains the mainstay of treatment for pediatric obstructive sleep apnea. Sometimes an adenoidectomy alone or a tonsillectomy alone may help relieve obstruction.

 

At what age is it safe to perform these procedures?

No age is a contraindication for surgery if the conditions that require it exist.

The usual age at which a tonsillectomy and adenoidectomy is performed is between 4 and 7 years. Surgery in very young children should preferably be performed in an institution that has facilities for pediatric intensive care.

 

Should children be monitored in hospital overnight after a tonsillectomy for sleep apnea?

Most can go home if they meet hospital discharge criteria. Very young children and those considered as being in the high risk category (your doctor will tell you) are usually observed overnight.

 

What are the common complications of this procedure?

  • Airway obstruction due to swelling of the tissues or excessive drowsiness
  • Dehydration especially in young children
  • Bleeding - early and delayed
  • Change in voice
  • Nasal regurgitation

 

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